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This Wikipedia page provides a comprehensive overview of the disease, covering its causes, symptoms, diagnosis, treatment options, prognosis, and preventive measures. The page explains that retinoblastoma is caused by mutations in the RB1 gene, which is responsible for controlling cell growth in the retina. These mutations can be inherited or occur spontaneously. Symptoms of the disease include a white pupil reflex, eye pain, and redness, while risk factors include a family history of retinoblastoma or certain genetic conditions. Diagnosis of retinoblastoma typically involves a thorough eye examination, imaging tests, and a biopsy. The staging of the disease, which determines the extent of its spread, is also explained. The page goes on to discuss various treatment options, including chemotherapy, radiation therapy, laser therapy, cryotherapy, and surgery. It emphasizes the importance of a multidisciplinary team in providing personalized treatment plans for each patient. Prognosis for retinoblastoma varies depending on factors such as the stage and location of the tumor, age at diagnosis, and the presence of genetic mutations. The page highlights the importance of early detection and timely intervention for improving outcomes. It also mentions the potential long-term complications of the disease, such as vision loss and risk of additional tumors. Preventing retinoblastoma in individuals with a genetic predisposition is addressed, including genetic counseling and screening strategies. The page also provides information on support services and organizations that help patients and families dealing with retinoblastoma. Overall, this Wikipedia page provides a comprehensive and detailed overview of retinoblastoma, serving as a valuable resource for understanding the disease, its diagnosis, treatment options, and preventive measures.