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This Wikipedia page provides an in-depth overview of anticoagulants, including their history, mechanism of action, types, and clinical uses. The page begins with a brief introduction to the concept of blood clotting and the importance of maintaining a delicate balance in the coagulation process. It then delves into the historical development of anticoagulants, starting with the discovery of heparin in the early 20th century and the subsequent creation of various anticoagulant drugs. The mechanism of action section explains how anticoagulants work to inhibit clot formation, emphasizing different targets in the coagulation cascade such as thrombin or factor Xa. It also highlights the importance of coagulation tests, such as the prothrombin time (PT) and activated partial thromboplastin time (aPTT), in monitoring anticoagulant therapy. The page further explores the different types of anticoagulants, including oral agents like warfarin, direct oral anticoagulants (DOACs), and parenteral anticoagulants such as heparin and low molecular weight heparins (LMWHs). Each class is described in detail, with information on their pharmacokinetics, dosing, and side effects. Clinical uses of anticoagulants are a significant focus of the page, with detailed explanations of their indications in various medical conditions, including atrial fibrillation, venous thromboembolism, deep vein thrombosis, and pulmonary embolism. The page also sheds light on anticoagulant use during pregnancy, in children, and during surgeries. Furthermore, the page provides a comprehensive overview of the risks and complications associated with anticoagulant therapy, such as bleeding events and interactions with other medications. It concludes with a discussion on the future direction of anticoagulation therapy, including emerging novel agents and potential advancements in the field. Overall, this Wikipedia page offers a comprehensive and detailed resource on anticoagulants, making it an invaluable tool for anyone seeking information on the topic.