Cohen could follow Buffett's playbook to build enormous value at GameStop, Burry said. A pet-supplies entrepreneur turned video-game retailer CEO who's been dubbed the "Meme King" might seem an unlikely candidate for the next Warren Buffett.

A trader works as a screen displays the trading information for GameStop on the floor at the New York Stock Exchange. The GameStop stock frenzy and the retail trading revolution it created five years ago were fueled in part by a financial malaise among younger investors, according to experts.